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5 Facts you should know about
Hemophagocytic lymphohistiocytosis (HLH)
1
A life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages
2
HLH clinically manifests with fever, enlargement of the liver and spleen, enlarged lymph nodes, yellow discoloration of the skin and eyes, and a rash
3
It is classified as one of the cytokine storm syndromes
4
Laboratory findings may include elevated triglyceride levels, low fibrinogen levels, transaminitis, and elevated ferritin levels
5
The onset of HLH occurs under the age of one year in approximately 70% of cases
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